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Not only its sum and also the practical Qualities of Hb influence efficiency. This is certainly illustrated via the observation that a heightened Hb-O2 affinity favors O2 loading from the lung and survival within an hypoxic environment (Eaton et al., 1974; Hebbel et al., 1978), While a diminished Hb-O2 affinity favors the release of O2 in the Hb mo